| Mesua ferrea (Nagkesar) |
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| Mesua ferrea is medium sized to large evergreen tree with very hard, strong and long wood. It is common in wet zone of Srilanka, Assam, southern China and peninsula. Mesua ferrea shows anti-inflammatory and antiseptic activity. Almost every part of the tree has therapeutic value in one or another disorder. The flowers are useful in medical conditions like asthma, leprosy, cough, fever and impotency. Dried flowers are useful in bleeding hemorrhoids and dysentery with mucus. Fresh flowers are useful in itching, nausea, bleeding piles, metrorrhage. The volatile oil extracted from plant can be used for sores, scabies, wounds, and rheumatism. |
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| Major Chemical Constituents: |
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Mesuol, Mesuone, and kernel and sell oils are major chemical constituents of Mesua ferrea having various clinically important properties. |
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| Pharmacological Actions: |
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| Bleeding control and reduces Itching: 1,2 |
| Mesua ferrea also reported as wound healing and control bleeding in the different authentic database addition to that it stabilizes mast cells and there by controlling histamine release it exerts anti-inflammatory effect as well reduced itching. |
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| Analgesic activity: 5 |
| The study shown that the extracts of Mesua ferrea administered orally to the mice produces significant antinociceptive action against chemically induced nociceptive pain. |
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| Herb Drug interactions: |
| There is not any known evidence of interaction of Mesua ferrea with other drug |
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| Safety: |
| No information about toxicity of this drug is available. |
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| References: |
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Constituents of Mesua ferrea. Fitoterapia. 1998; 69: 291-304 |
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Medicinal Plants of East and Southeast Asia. MIT Press, Cambridge, MA, 1980. |
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Chakraborty DP, Purkayastha M, and Bose PK. On the antibiotic properties of some constituents of Mesua ferrea Linn. Department of chemistry, Bose Institute, 1958. |
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Mazumder R, Dastidar S, Basu S, Mazumder S, Singh S. Antibacterial potentiality of Mesua ferrea Linn. Flowers. Phytotherapy research, 2004; 18(10): 824-826. |
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Hassan MT, Ali MS, Alimuzzaman M, and Raihan SZ, Analgesic Activity of Mesua ferrea Linn. Dhaka Univ. J. Pharm. Sci. 5(1-2): 73-75 |
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